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Diagnosis

Ambient Refractive Index-Responsive Gold Nanoparticle-Quantum Dot Hybrid Fluorescence Biosensor for Quantitative Detection of Influenza A 

 

 


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This lateral-flow biosensor uses a silica-protected gold-nanoparticle/quantum-dot hybrid probe (AuNP@SiO₂/QD) in which the gold core quenches quantum-dot fluorescence until target binding occurs. Antibody–antigen recognition relieves the quenching and restores a bright signal, enabling sensitive, quantitative point-of-care detection of Influenza A. 

Quantum Dot-Encapsulated Polystyrene–Poly(acrylic acid) Beads as a Fluorescence Biosensor for Quantitative Detection of Influenza A 

 



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Quantum dots packed into polymer (PS-PAA) beads create ultra-bright fluorescent probes for lateral-flow influenza testing. Antibody-functionalized beads bind the virus specifically while an AI-assisted algorithm corrects and quantifies the signal, pushing sensitivity to the picogram level (LOD ≈ 1 pg/mL) and turning a simple test strip into a precise quantitative diagnostic.

 

 

Antibody-Conjugated InP Quantum Bead Platform for Stable Fluorescence and Quantitative Virus Detection

 


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Built from cadmium-free indium phosphide (InP) quantum dots, these self-assembled quantum beads deliver exceptionally stable fluorescence over time, outperforming both bare InP dots and conventional Cd-based quantum dots. Antibody conjugation yields a robust, heavy-metal-free probe for sensitive and reliably quantitative virus detection by lateral flow immunoassay (LFIA).