강원대학교 나노바이오공학 연구실

Publication

Publication

Publication

Articles

2026
38
Engineering cationic nanovaccines to enable precision immunotherapy in infectious diseases and cancer

Subin Lee†, Jeongeun Kim†, Beomsu Kim, Byeong-su Kim, Jinseob Shin, Jaewon Choi, Minse Kim, Young Ho Seo, Byeong Hee Kim, Kwang Suk Lim, Suk-Jin Ha, Sun Eun Choi* and Hyun-Ouk Kim*
- Journal :
  Discover Applied Sciences (Springer)
- Year :
  2026
- Page :
  49
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2025
37
Polymer- and Lipid-Based Nanostructures for Wound Healing with Barrier-Resolved Design

Eunsoo Cho†, Soyeon Yun†, Subin Lee, Minse Kim, Jaewon Choi, Sun Eun Choi, Kwang Suk Lim, Suk-Jin Ha, Jang-Hyuk Yun* and Hyun-Ouk Kim*
- Journal :
  Pharmaceutics
- Year :
  2025
- Volume and Issue :
  17(11)
- Page :
  40
View More
36
CliCAR: A non-genetic CAR engineering strategy to empower NK cells for targeted cancer immunotherapy

Su Yeon Lim†, Yeongbeom Kim, Seungmin Han, Hyun-Ouk Kim, Suk-Jin Ha, Jeong-Ann Park, Jina Yun, Sehyun Chae, Young-Wook Won*, Kwang Suk Lim**
- Journal :
  Biomedicine & Pharmacotherapy
- Year :
  2025
- Page :
  14
View More
35
Advances of PCL, PLA, and PLGA-Based Technologies for Anticancer Drug Delivery

Yeongbeom Kim†, ,Jaewoo Kwak†, Minyeong Lim, Su Yeon Lim, Sehyun Chae, Suk-Jin Ha, Young-Wook Won, Hyun-Ouk Kim* and Kwang Suk Lim*
- Journal :
  Pharmaceutics
- Year :
  2025
- Volume and Issue :
  17(10)
- Page :
  27
View More
34
Surface Engineering of Natural Killer Cells with Lipid-Based Antibody Capture Platform for Targeted Chemoimmunotherapy

Su Yeon Lim†, Yeongbeom Kim†, Hongbin Kim, Seungmin Han, Jina Yun, Hyun-Ouk Kim, Suk-Jin Ha, Sehyun Chae, Young-Wook Won* and Kwang Suk Lim*
- Journal :
  Pharmaceutics
- Year :
  2025
- Volume and Issue :
  17(10)
- Page :
  16
View More
33
Physiological Barriers to Nucleic Acid Therapeutics and Engi-neering Strategies for Lipid Nanoparticle Design, Optimization, and Clinical Translation

Yerim Kim†, ,Jisu Park†, ,Jaewon Choi, Minse Kim, Gyeongsu Seo,, Jeongeun Kim, Jeong-Ann Park, Kwang Suk Lim, Suk-Jin Ha and Hyun-Ouk Kim*
- Journal :
  Pharmaceutics
- Year :
  2025
- Volume and Issue :
  17(10)
- Page :
  36
View More
32
3D Bioprinted Neural Tissues: Emerging Strategies for Regeneration and Disease Modeling

Taekyung Choi, Jinseok Park, ,Suvin Lee, Hee-Jae Jeon, Byeong Hee Kim, Hyun-Ouk Kim*, and Hyungseok Lee*
- Journal :
  Pharmaceutics
- Year :
  2025
- Volume and Issue :
  17(9)
- Page :
  26
View More
31
Combination Strategies with HSP90 Inhibitors in Cancer Therapy: Mechanisms, Challenges, and Future Perspectives

Yeongbeom Kimi† ; Su Yeon Lim† ; Hyun-Ouk Kim ; Suk-Jin Ha ; Jeong-Ann Park ; Young-Wook Won ; Sehyun Chae ; Kwang Suk Lim*
- Journal :
  Pharmaceuticals
- Year :
  2025
- Volume and Issue :
  18(8)
- Page :
  1083
View More
30
Bio-drone Platform for Based GBM Diagnosis and Treatment: Current and Future Prospects

Hwunjae Lee†* ; Hyun-Ouk Kim†*
- Journal :
  Korean Society for Biotechnology and Bioengineering
- Year :
  2025
- Volume and Issue :
  40(2)
- Page :
  99-104
View More
29
Development of Monoclonal Antibody Application in Cancer Therapy: The Roles of ADCC, CDC, ADCP, and ADC

Chanho Park† ; Jaewoo Kwak† ; Su Yeon Lim† ; Hyun-Ouk Kim* ; Kwang Suk Lim*
- Journal :
  Korean Society for Biotechnology and Bioengineering
- Year :
  2025
- Volume and Issue :
  40(1)
- Page :
  22-31
View More
28
Enhanced Tumor Therapy Utilizing Lipid-Based Drug Delivery Systems

YIhyeon Kim† ; Chaeseon kim† ; Hyun-Ouk Kim* ; Kwang Suk Lim*
- Journal :
  Korean Society for Biotechnology and Bioengineering
- Year :
  2025
- Volume and Issue :
  40(1)
- Page :
  1-9
View More
2024
27
A facile approach to microplastic identification and quantification using differential scanning calorimetry

Jooyoung Lee † ; Soyeong Yoon ; Taesoon Jang ; Jin-Hyuk Choi ; Narae Kim ; Hyun-Ouk Kim ; Kwang Suk Lim ; Suk-Jin Ha ; Jeong-Ann Park *
- Journal :
  Science of The Total Environment
- Year :
  2024
- Volume and Issue :
  957
- Page :
  177456
View More
26
Application of metal-organic frameworks for photocatalytic degradation of microplastics: Design, challenges, and scope

Minse kim † ; Yu-Rim Ahn † ; Soyeong Yoon † ; Jaewon Choi ; Hongbin Kim ; Kwang suk Lim ; Suk-Jin Ha ; Jeong-Ann Park * ; Hyun-Ouk Kim*
- Journal :
  Chemosphere
- Year :
  2024
- Volume and Issue :
  366
- Page :
  143518
View More
25
Advances in Nanoparticles as Non-Viral Vectors for Efficient Delivery of CRISPR/Cas9

Minse kim † ; Youngwoo Hwang † ; Seongyu Lim ; Hyeong-Ki Jang* ; Hyun-Ouk Kim*
- Journal :
  Pharmaceutics
- Year :
  2024
- Volume and Issue :
  16(9)
- Page :
  1197
View More
24
Biodegradation of Low-Density Polyethylene by Acinetobacter guillouiae PL211 Ioslated from the Waste Treatment Facility

Yejin Kim † ; Jang-Sub Lee ; Jeong-Ann Park ; Hyun-Ouk Kim ; Kwang Suk Lim ; Suk-Jin Ha*
- Journal :
  Microbiology and Biotechnology Letters
- Year :
  2024
- Volume and Issue :
  52(2)
- Page :
  189-794
View More
23
Efficient biodegradation of low-density polyethylene by Pseudomonas plecoglossicida SYp2123 was observed through FT-IR and FE-SEM analysis

Yejin Kim † ; Yeon-Hwa Kim ; Ye-Rim Shin ; Su-Yeong Choi ; Jeong-Ann Park ; Hyun-Ouk Kim ; Kwang Suk Lim ; Suk-Jin Ha*
- Journal :
  Biotechnology and Bioprocess Engineering
- Year :
  2024
- Volume and Issue :
  29
- Page :
  743-750
View More
22
Development of Tat-fused drug binding protein to improve anti-cancer effect of mammalian target of rapamycin inhibitors

Su Yeon Lim†; Sugyeong Kim ; Hongbin Kim ; Hyun-Ouk Kim ; Suk-Jin Ha ; Kwang Suk Lim*
- Journal :
  Biotechnology and Bioprocess Engineering
- Year :
  2024
- Volume and Issue :
  29
- Page :
  303-312
View More
21
Mammalian Cell Membrane Hybrid Polymersomes for mRNA Delivery

SoJin Shin † ; Yu-Rim Ahn † ; Minse Kim ; Jaewon Choi ; HakSeon Kim ; Hyun-Ouk Kim*
- Journal :
  ACS Applied Materials & Interfaces
- Year :
  2024
- Volume and Issue :
  16
- Page :
  20232-20244
View More
20
Recent advances in microbial and enzymatic engineering for the biodegradation of micro- and nanoplastics

Jaewon Choi † ; Hongbin Kim † ; Yu-Rim Ahn ; Minse Kim ; Seona Yu ; Nanhyeon Kim ; Su Yeon Lim ; Jeong-Ann Park ; Suk-Jin Ha ; KwangSuk Lim* ; Hyun-Ouk Kim*
- Journal :
  RSC Advances
- Year :
  2024
- Volume and Issue :
  14(14)
- Page :
  9943-9966
View More
19
Dual‑targeted nano‑encapsulation of neonatal porcine islet‑like cell clusters with triiodothyronine-loaded bifuntionalpolymersomes

Sang Hoon Lee † ; Minse Kim † ; Eun-jin Lee ; Sun mi Ahn ; Yu-Rim Ahn ; Jaewon Choi ; Jung-Taek Kang* ; Hyun-Ouk Kim*
- Journal :
  Discover Nano
- Year :
  2024
- Volume and Issue :
  19(1)
- Page :
  23
View More
2023
18
Charge-Complementary Polymersomes for Enhanced mRNA Delivery

HakSeon Kim† ; Yu-Rim Ahn† ; Minse Kim ; Jaewon Choi ; SoJin Shin ; Hyun-Ouk Kim*
- Journal :
  Pharmaceutics
- Year :
  2023
- Volume and Issue :
  15(12)
- Page :
  2781
View More
17
Adsorption behavior of triclosan on microplastics and their combined acute toxicity to D. magna

Soyeong Yoon† ; Jooyoung Lee ; Mingi Ko ; Taesoon Jan ; Kwang Suk Lim ; Hyun-Ouk Kim ; Suk-Jin Ha ; Jeon-Ann Park†
- Journal :
  Science of The Total Environment
- Year :
  2023
- Volume and Issue :
  880
- Page :
  163290
View More
2022
16
Ulmus davidiana var. japonica Extracts Suppress Lipopolysaccharide-Induced Apoptosis Through Intracellular Calcium Modulation in U937 Macrophages

Jang-Hyuk Yun†, Hyun-Ouk Kim†, Jae-Hun Jeong, Yerin Min, Kwang-Hyun Park *, Chuanling Si * and Sun-Eun Choi *
- Journal :
  Frontiers in Energy Research
- Year :
  2022
- Volume and Issue :
  10
- Page :
  820330
View More
2021
15
Optimization of Nano-encapsulation on Neonatal Porcine Islet-like Cell Clusters Using Polymersomes

Sang Hoon Lee† ; Hyun‑Ouk Kim† and Jung‑Taek Kang
- Journal :
  Nanoscale Research Letter
- Year :
  2021
- Volume and Issue :
  16(29)
- Page :
  29
View More
14
A 60% Edible Ethanolic Extract of Ulmus davidiana Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis

Jeongho Park† ; Hyun-Ouk Kim† ; Kwang-Hyun Park† ; Myung-Bok Wie ; Sun-Eun Choi* ; Jang-Hyuk Yun*
- Journal :
  Molecules
- Year :
  2021
- Volume and Issue :
  26(4)
- Page :
  781
View More
2020
13
Porous gold nanoparticles for attenuating infectivity of influenza A virus

Jinyoung Kim† ; Minjoo Yeom† ; Taeksu Lee ; Hyun-Ouk Kim ; Woonsung Na ; Aram Kang ; Jong-Woo Lim ; Geunseon Park ; Chaewon Park ; Daesub Song* ; Seungjoo Haam*
- Journal :
  Journal of Nanobiotechnology
- Year :
  2020
- Volume and Issue :
  18
- Page :
  54
View More
12
Cell-mimic polymersome-shielded islets for long-term immune protection of neonatal porcine islet-like cell clusters

Hyun-Ouk Kim† ; Sang Hoon Lee† ; Woonsung Na ; Jong-Woo Lim ; Geunseon Park ; Chaewon Park ; Hwunjae Lee ; Aram Kang ; Seungjoo Haam ; Inho Choi ; Jung-Taek Kang* ; Daesub Song*
- Journal :
  Journal of Materials Chemistry B
- Year :
  2020
- Volume and Issue :
  8(12)
- Page :
  2476-2482
View More
2019
11
Bandgap-controlled hollow polyaniline nanostructures synthesized by Mn-dependent nano-confined polymerization

Jihye Choi†* ; Byunghoon Kang ; Hyun-Ouk Kim ; Jin-Suck Suh ; Seungjoo Haam* ; Jaemoon Yang*
- Journal :
  Nanoscale
- Year :
  2019
- Volume and Issue :
  11(5)
- Page :
  2434-2438
View More
2018
10
Efficient antiviral co-delivery using polymersomes by controlling the surface density of cell-targeting groups for influenza A virus treatment

Haejin Chun† ; Minjoo Yeom† ; Hyun Ouk Kim ; Jong Woo Lim ; Woonsung Na ; Geunseon Park ; Chaewon Park ; Aram Kang ; Dayeon Yun ; Jihye Kim ; Daesub Song* ; Seungjoo Haam*
- Journal :
  Polymer Chemistry
- Year :
  2018
- Volume and Issue :
  9(16)
- Page :
  2216-2123
View More
2017
9
Stent containing CD44-targeting polymeric prodrug nanoparticles that release paclitaxel and gemcitabine in a time interval-controlled manner for synergistic human biliary cancer therapy†

Dayeon Yun‡ ; Hyun-Ouk Kim‡ ; Hye Young Son ; Yuna Choi ; Ilkoo Noh ; Jong-Woo Lim ; Jihye Kim ; Haejin Chun ; Geunseon Park ; Dong Ki Lee ; Sung Il Jang ; Eunji Jang ; Yong-Min Huh* ; Seungjoo Haam
- Journal :
  Journal of Materials Chemistry B
- Year :
  2017
- Volume and Issue :
  5
- Page :
  6317-6324
View More
8
Reactive Oxygen Species-Regulating Polymersome as an Antiviral Agent against Influenza Virus

Hyun-Ouk Kim†, Minjoo Yeom†, Jihye Kim†, Aastha Kukreja, Woonsung Na, Jihye Choi, Aram Kang, Dayeon Yun, Jong-Woo Lim, Daesub Song*, and Seungjoo Haam*
- Journal :
  Small
- Year :
  2017
- Volume and Issue :
  13(32)
- Page :
  1700818
View More
2016
7
Magnetic Nanovector Enabling miRNA-34a Delivery for CD44 Suppression with Concurrent MR Imaging

Kim, Hyun-Ouk† ; Lee, HwunJae† ; Son, Hye-Young ; Lee, Sang-Bock ; Jang, Eunji ; Kang, Byunghoon ; Haam, Seungjoo ; Lim, Eun-Kyung* ; Huh, Yong-Min*
- Journal :
  Journal of Nanoscience and Nanotechnology
- Year :
  2016
- Volume and Issue :
  16(12)
- Page :
  12939-12946
View More
2015
6
Co-delivery of paclitaxel and gemcitabine via CD44-targeting nanocarriers as a prodrug with synergistic antitumor activity against human biliary cancer

Ilkoo Noh† ; Hyun-Ouk Kim ; Jihye Choi ; Yuna Choi ; Dong Ki Lee ; Yong-Min Huh* ; Seungjoo Haam*
- Journal :
  Biomaterials
- Year :
  2015
- Volume and Issue :
  53
- Page :
  763-774
View More
5
Pseudo metal generation via catalytic oxidative polymerization on the surface of reactive template for redox switched off-on photothermal therapy

Seo Ryung Bae† ; Jihye Choi ; Hyun Ouk Kim ; Byunghoon Kang ; Myeong Hoon Kim ; Seungmin Han ; Ilkoo Noh ; Jong Woo Lim ; Jin Suk Suh ; Yong Min Huh* ; Seungjoo Haam*
- Journal :
  Journal of Materials Chemistry B
- Year :
  2015
- Volume and Issue :
  3(3)
- Page :
  505-513
View More
2014
4
Aptamer-conjugated gold nanorod for photothermal ablation of epidermal growth factor receptor-overexpressed epithelial cancer

Jihye Choi† ; Yeonji Park ; Eun Bi Choi ; Hyun-Ouk Kim ; Dong Joo Kim ; Yoochan Hong ; Sung-Ho Ryu ; Jung Hwan Lee ; Jin-Suck Suh ; Jaemoon Yang ; Yong-Min Huh* ; Seungjoo Haam*
- Journal :
  Journal of Materials Chemistry B
- Year :
  2014
- Volume and Issue :
  19(5)
- Page :
  051203
View More
2013
3
π-Hyaluronan nanocarriers for CD44-targeted and pH-boosted aromatic drug delivery

Eunji Jang† ; Eun-Kyung Lim ; Yuna Choi ; Eunjung Kim ; Hyun-Ouk Kim ; Dong-Joo Kim ; Jin-Suck Suh ; Yong-Min Huh* ; Seungjoo Haam*
- Journal :
  Journal of Materials Chemistry B
- Year :
  2013
- Volume and Issue :
  1(41)
- Page :
  5686-5693
View More
2
Hyaluronic acid receptor-targetable imidazolizednanovectors for induction of gastric cancer cell death by RNA interference

Eunjung Kim† ; Hyun-Ouk Kim ; Jaemoon Yang ; Hyun-Ouk Kim ; Yonghee An ; Eun-Kyung Lim ; Gyudo Lee ; Taeyun Kwon ; Jae-Ho Cheong ; Jin-Suck Suh ; Yong-Min Huh* ; Seungjoo Haam*
- Journal :
  Biomaterials
- Year :
  2013
- Volume and Issue :
  34(17)
- Page :
  4327-4338
View More
1
A Biodegradable Polymersome Containing Bcl-xL siRNA and Doxorubicin as a Dual Delivery Vehicle for a Synergistic Anticancer Effect

Hyun-Ouk Kim† ; Eunjung Kim ; Yonghee An ; Jihye Choi ; Eunji Jang ; Eun Bi Choi ; Aastha Kukreja ; Myeong-Hoon Kim ; Byunghoon Kang ; Dong-Joo Kim ; Jin-Suck Suh ; Yong-Min Huh* ; Seungjoo Haam*
- Journal :
  Macromolecular Biosicience
- Year :
  2013
- Volume and Issue :
  13(6)
- Page :
  745-754
View More

Publication

Articles

Articles

Engineering cationic nanovaccines to enable precision immunotherapy in infectious diseases and cancer

Polymer- and Lipid-Based Nanostructures for Wound Healing with Barrier-Resolved Design

CliCAR: A non-genetic CAR engineering strategy to empower NK cells for targeted cancer immunotherapy

Advances of PCL, PLA, and PLGA-Based Technologies for Anticancer Drug Delivery

Surface Engineering of Natural Killer Cells with Lipid-Based Antibody Capture Platform for Targeted Chemoimmunotherapy

Physiological Barriers to Nucleic Acid Therapeutics and Engi-neering Strategies for Lipid Nanoparticle Design, Optimization, and Clinical Translation

3D Bioprinted Neural Tissues: Emerging Strategies for Regeneration and Disease Modeling

Combination Strategies with HSP90 Inhibitors in Cancer Therapy: Mechanisms, Challenges, and Future Perspectives

Bio-drone Platform for Based GBM Diagnosis and Treatment: Current and Future Prospects

Development of Monoclonal Antibody Application in Cancer Therapy: The Roles of ADCC, CDC, ADCP, and ADC

Enhanced Tumor Therapy Utilizing Lipid-Based Drug Delivery Systems

A facile approach to microplastic identification and quantification using differential scanning calorimetry

Application of metal-organic frameworks for photocatalytic degradation of microplastics: Design, challenges, and scope

Advances in Nanoparticles as Non-Viral Vectors for Efficient Delivery of CRISPR&#x2F;Cas9

Biodegradation of Low-Density Polyethylene by Acinetobacter guillouiae PL211 Ioslated from the Waste Treatment Facility

Efficient biodegradation of low-density polyethylene by Pseudomonas plecoglossicida SYp2123 was observed through FT-IR and FE-SEM analysis

Development of Tat-fused drug binding protein to improve anti-cancer effect of mammalian target of rapamycin inhibitors

Mammalian Cell Membrane Hybrid Polymersomes for mRNA Delivery

Recent advances in microbial and enzymatic engineering for the biodegradation of micro- and nanoplastics

Dual‑targeted nano‑encapsulation of neonatal porcine islet‑like cell clusters with triiodothyronine-loaded bifuntionalpolymersomes

Charge-Complementary Polymersomes for Enhanced mRNA Delivery

Adsorption behavior of triclosan on microplastics and their combined acute toxicity to D. magna

Ulmus davidiana var. japonica Extracts Suppress Lipopolysaccharide-Induced Apoptosis Through Intracellular Calcium Modulation in U937 Macrophages

Optimization of Nano-encapsulation on Neonatal Porcine Islet-like Cell Clusters Using Polymersomes

A 60% Edible Ethanolic Extract of Ulmus davidiana Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis

Porous gold nanoparticles for attenuating infectivity of influenza A virus

Cell-mimic polymersome-shielded islets for long-term immune protection of neonatal porcine islet-like cell clusters

Bandgap-controlled hollow polyaniline nanostructures synthesized by Mn-dependent nano-confined polymerization

Efficient antiviral co-delivery using polymersomes by controlling the surface density of cell-targeting groups for influenza A virus treatment

Stent containing CD44-targeting polymeric prodrug nanoparticles that release paclitaxel and gemcitabine in a time interval-controlled manner for synergistic human biliary cancer therapy†

Reactive Oxygen Species-Regulating Polymersome as an Antiviral Agent against Influenza Virus

Magnetic Nanovector Enabling miRNA-34a Delivery for CD44 Suppression with Concurrent MR Imaging

Co-delivery of paclitaxel and gemcitabine via CD44-targeting nanocarriers as a prodrug with synergistic antitumor activity against human biliary cancer

Pseudo metal generation via catalytic oxidative polymerization on the surface of reactive template for redox switched off-on photothermal therapy

Aptamer-conjugated gold nanorod for photothermal ablation of epidermal growth factor receptor-overexpressed epithelial cancer

π-Hyaluronan nanocarriers for CD44-targeted and pH-boosted aromatic drug delivery

Hyaluronic acid receptor-targetable imidazolizednanovectors for induction of gastric cancer cell death by RNA interference

A Biodegradable Polymersome Containing Bcl-xL siRNA and Doxorubicin as a Dual Delivery Vehicle for a Synergistic Anticancer Effect

Advances in Nanoparticles as Non-Viral Vectors for Efficient Delivery of CRISPR/Cas9